However, results from a 2017 study indicate that CBD and THC can lead to less acute pain and less intense pain for people with migraine. In this two-phase study, some participants took a combination of two compounds. One compound contained 9 percent CBD and almost no THC. The other compound contained 19 percent THC.
In phase I, there was no effect on pain when the doses were under 100 mg. When the doses were increased to 200 mg, acute pain fell by 55 percent. In phase II, participants who received the combination of CBD and THC compounds saw the frequency of their migraine attacks fall by 40.
The daily dose was 200 mg. The combination of compounds was slightly more effective than 25 mg of amitriptyline, a tricyclic antidepressant. Amitriptyline reduced migraine attacks by 40. 1 percent in study participants. Participants with cluster headaches also found pain relief with the combination of CBD and THC compounds, but only if they’d had a childhood history of migraine.
However, certain side effects are possible, such as:fatiguediarrheachanges in appetitechanges in weightCBD may interact with: certain over-the-counter (OTC) drugsprescription medicationsdietary supplements Proceed with caution if any of your medications or supplements contain a “grapefruit warning.” Grapefruit and CBD both interfere with enzymes that are crucial to drug metabolism. Like other drugs and supplements, CBD may also increase your risk of liver toxicity.
However, some of the mice had been force-fed very large amounts of the CBD-rich cannabis extract. While there isn’t conclusive data to support CBD or CBD oil as the preferred method of pain management, researchers agree that these types of products have a lot of potential. CBD products might be able to offer relief for many people who have chronic pain, all without causing drug intoxication and dependence.
They can help you determine a starting dosage that’s right for you. Hemp-derived CBD products (with less than 0. 3 percent THC) are legal on the federal level, but are still illegal under some state laws. Marijuana-derived CBD products are illegal on the federal level, but are legal under some state laws.
Take a look at the label on any over-the-counter pain reliever and you can easily figure out how much you’re supposed to take for your symptoms. Finding the right dose of cannabidiol (CBD) for pain relief, however, isn’t that simple. Enthusiasts rave about CBD’s potential to ease pain, reduce inflammation, relieve anxiety and promote sleep.
There are very few human studies on CBD, and those that have been done include doses that are all over the map: In some studies, patients used 5 mg of CBD; in others, they took as much as 600 mg. To further add to the confusion, CBD comes in a number of forms — oils and tinctures, creams and lotions, pills, vaping, and edibles — and each one has differences in terms of bioavailability (the percent of active ingredient that gets into your bloodstream).
“Ultimately, it’s trial and error, but you have to go about it in a methodical way.” Here are some tips to guide you on how to find the right CBD dosage for your pain relief and other symptoms. Many factors, such as your body mass index (BMI), specific health condition(s) you have, medications you take, your health history, and the form of CBD you plan to use can influence how much CBD you may need to treat your symptoms.
“I wouldn’t recommend starting CBD without the supervision of a physician,” says Dr. Patel, author of The CBD Solution. “Many times people purchase a CBD product, try a dose that that doesn’t work for them, switch products and spin their wheels. Or, worse, they develop side effects.” Ask your rheumatologist or primary care provider to recommend an expert, or find an expert near you by searching the directory of members of the Society of Cannabis Clinicians or the database maintained by your state’s medical marijuana program (if it has one).
Now what? The answer depends on which form of CBD you take. Figuring out how much CBD is in capsules or gummies is simple — just read the supplement facts section on the label. (If it says 10 mg of CBD per capsule, you’d take three capsules to get your 30 mg of CBD a day.) Oils and tinctures can be trickier because the packaging often states the amount of CBD in the entire bottle, not in a dropper.
When it comes to CBD in topical form (creams, lotions, and salves), you’ll probably see the total amount of CBD in the container listed on the label. You’ll then have to divide that total by the number of millimeters in the package to determine how much is in each milliliter.