According to a 2015 study published in Neurotherapeutics, CBD influences many other receptor systems in our body and will influence the ECS in combination with other cannabinoids. For example, CBD can increase the body’s levels of anandamide, a compound associated with regulating pain, which can reduce pain perception and improve mood.
For more information and resources on CBD and CBD products, please visit our dedicated hub. Different varieties of cannabis plants — such as hemp and marijuana — contain different levels of chemical compounds. How people breed the plant affects the CBD levels. Most CBD oil comes from industrial hemp, which usually has a higher CBD content than marijuana.
The extract is then added to a carrier oil and called CBD oil. CBD oil comes in many different strengths, and people use it in various ways. It is best to discuss CBD oil with a doctor before using it. According to the National Centers for Complementary and Integrative Health (NCCIH), some evidence suggests that cannabis or CBD could have modest benefits for chronic pain.
A 2020 review reports that CBD could have benefits for relieving chronic pain, improving sleep, and reducing inflammation, but that these effects are condition-specific. More evidence is needed to determine the therapeutic potential of CBD and to determine safe and effective dosages for pain. Based on the current research, here are some possible benefits of CBD oil:Neuropathic pain is pain caused by damage to the nerves.
A 2017 review found that CBD helped with chronic neuropathy pain in humans. The researchers looked at 11 randomized controlled trials with 1,219 patients. However, a 2018 Cochrane review concluded that the potential benefits of cannabis-based medicine might be outweighed by its potential harms. This research looked into the effects of cannabis-derived medicines, including CBD, for chronic neuropathic pain.
More research is needed to understand the role of CBD in chronic neuropathic pain management, including the risks, benefits, and ideal dosages. A 2016 study in the European Journal of Pain used an animal model to see if CBD could help people with arthritis manage their pain. Researchers applied a topical gel containing CBD to rats with arthritis for 4 days.
People using CBD oil for arthritis may find relief from their pain, but more human studies need to be done to confirm these findings.Multiple sclerosis (MS) is an autoimmune condition that affects the entire body through the nerves and brain. Muscle spasms are one of the most common symptoms of MS.
The results are modest, but many people reported a reduction in symptoms. More studies on humans are needed to verify these results. The same report studied CBD use for general chronic pain. Researchers compiled the results of multiple systematic reviews covering dozens of trials and studies. Their research concluded that there is substantial evidence that cannabis is an effective treatment for chronic pain in adults.
This research suggests that using CBD can reduce pain and inflammation. The researchers also found that subjects were not likely to build up a tolerance to the effects of CBD, so they would not need to increase their dose over time. They noted that cannabinoids, such as CBD, could offer helpful new treatments for people with chronic pain.
These include:Although more research is required to confirm the benefits of CBD oil, it is shaping up as a potentially promising and versatile treatment. The Food and Drug Administration (FDA) have approved one form of CBD, called Epidiolex, to treat two rare forms of epilepsy and to treat seizures caused by a rare condition called tuberous sclerosis complex.
People should check their state’s laws and those of any place they intend to travel. They must keep in mind that the FDA do not approve or regulate nonprescription CBD products. As a result, labeling may be inaccurate. The FDA does not regulate CBD for most conditions. As a result, dosages are currently open to interpretation, and people should treat them with caution.
The FDA has approved a purified form of CBD for some types of epilepsy, with the brand name Epidiolex. People using this medication should follow the doctor’s advice about doses. Most people tolerate CBD oil well, but there are some possible side effects. According to a 2017 review in Cannabis and Cannabinoid Research, the most common side effects include:In addition, using CBD oil with other medications may make those medications more or less effective.
Further long-term studies will be helpful in determining any side effects CBD has on the body over time. Consult a doctor before using CBD, as it may interact with certain over-the-counter dietary supplements and medicines, as well as some prescription medications — especially those that warn against consuming grapefruit. CBD might also interfere with an enzyme called cytochrome P450 complex.